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IBCSG 57-18 TAXIS
OPBC-03 / SAKK 23/16 / IBCSG 57-18 / ABCSG-53 / GBG-101. Tailored AXIllary
Surgery with or without axillary lymph node dissection followed
by radiotherapy in patients with clinically node-positive breast
cancer (TAXIS).
A multicenter randomized phase III trial.
The removal of all lymph nodes in the armpit through conventional
axillary dissection has been standard care for all patients with breast
cancer for almost a century. In the nineties, the sentinel lymph node
(SLN) procedure, which involves the selective removal of the first
few lymph nodes in the lymphatic drainage system, was introduced
in clinical practice. Today, conventional axillary dissection is still
performed on many women with breast cancer that has spread to
the nodes. It is the cause for relevant morbidity in the form of
lymphedema, impairment of shoulder mobility, sensation disorders
and chronic pain in as much as one third of all women undergoing
the procedure.
The TAXIS trial will evaluate the optimal treatment for breast cancer
patients with confirmed nodal disease at first diagnosis in terms of
surgery and radiotherapy. In particular, it will investigate the value of
tailored axillary surgery (TAS), a new technique that aims at
selectively removing the positive lymph nodes. TAS is a promising
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patients by avoiding surgical overtreatment.
This trial has the potential to establish a new worldwide treatment
standard with hopefully less side effects and a better quality of life,
while keeping the same efficacy as provided by radical surgery.
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A multicenter randomized phase III trial.
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tailored axillary surgery (TAS), a new technique that aims at
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A multicenter randomized phase III trial.
The removal of all lymph nodes in the armpit through conventional
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selectively removing the positive lymph nodes. TAS is a promising
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Project Management
Mariacarla Andreozzi, Phone: +41 61 328 42 98
Maite Goldschmidt, Phone: +41 61 328 45 72
Alexandra Schulz, Phone: +41 61 328 54 01
Backup fax: +41 61 265 94 10
This email address is being protected from spambots. You need JavaScript enabled to view it.
ETOP IBCSG Partners Foundation
1500
"
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Project Management
Mariacarla Andreozzi, Phone: +41 61 328 42 98
Maite Goldschmidt, Phone: +41 61 328 45 72
Alexandra Schulz, Phone: +41 61 328 54 01
Backup fax: +41 61 265 94 10
taxis.trial@usb.ch
ETOP IBCSG Partners Foundation
1500
"
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ETOP IBCSG Partners Foundation
Effingerstrasse 33
3008 Bern, Switzerland
Contact
Phone: +41 31 511 94 00
E-mail: contact@etop.ibcsg.org
Donating & Supporting